Deep sea sediment budgets can be used to constrain erosion rates in the neighboring continents from which the material was derived. Here we construct a sediment budget for the Transkei Basin, offshore South Africa using an existing seismic reflection survey and dated by correlation of seismic attributes to dated sections in nearby basins. Backstripping of the sections reveals that sediment accumulation rates fell from 110 to 11 Ma, with a possible period of rapid accumulation from 36 to 34 Ma that may be driven by strengthening of the Antarctic Bottom Water (AABW). The long term trend is linked to erosional degradation of the onshore continental escarpment, formed as a consequence of continental break-up. No change is noted at 30 Ma, coincident with proposed uplift of southern Africa driven by plume activity. The basin shows a significant increase in sediment accumulation after 11 Ma, which we interpret to reflect strengthening and rerouting of the AABW from the south into Transkei Basin, as a far field effect of the start of closure of the Indonesian Throughflow.