2-Hydroxy-luisol A, a New Quinone-derived Tetraol from a Marine Streptomyces sp and Oxidation Products of Luisol A


Contact
hlaatsc [ at ] gwdg.de

Abstract

Abstract: In addition to luisol A (1a), luisol B (2), and aloesaponarin II, the marine streptomycete B7617 produced a new derivative of la, 2-hydroxy-luisol A (1b). In an attempt to increase the biological activity, luisol A (1a) was oxidized and delivered with Jones reagent or by Swern oxidation the derivatives 3a/3b and 4a/4b, respectively, but none of these compounds showed antimicrobial or cytotoxic activities. All structure elucidations are based on 2D NMR analyses or were derived by comparison with published data.



Item Type
Article
Authors
Divisions
Programs
Peer revision
ISI/Scopus peer-reviewed
Publication Status
Published
Eprint ID
30616
Cite as
Fotso, S. , Yao, C. , Helmke, E. and Laatsch, H. (2011): 2-Hydroxy-luisol A, a New Quinone-derived Tetraol from a Marine Streptomyces sp and Oxidation Products of Luisol A , ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 66 (6), pp. 629-634 .


Share

Research Platforms
N/A

Campaigns


Actions
Edit Item Edit Item