Seventeen specimens of Notiax santarita sp. nov. were collected in the Beagle Channel in southernmost Chile during the Joint Chilean-German-Italian "Victor Hensen" Campaign in 1994 and the Chilean expedition "Cimar Fiordo III" in 1997. These specimens are the first Callianassidae that are recorded south of 46 degree S in Chile and represent the second species of the genus Notiax found in America. This callianassid, herein described as a new species, has been compared with the second species of the genus, Notiax brachyophthalma, known from the Chilean and Argentine coasts.