Density-driven mass movement deposits (MMDs) were mapped throughout the Quaternary sedimentary record of Lake El'gygytgyn (NE Siberia) using high-resolution acoustic data. Three different acoustic facies types were identified in the lake: (1) pelagic sediment, (2) plastic flow deposits and (3) turbidites. Deposits from plastic flows are dominantly present proximal to the lakes' slopes, whereas deposits from turbidity currents occur more spatially distributed. During glacial times, the distribution of MMDs was more uniform, while during interglacial periods, MMDs were deposited predominantly close to the slope of the northwestern area. Furthermore, the overall number of MMDs and accumulated sediment volume significantly varies between glacial/interglacial periods. About 1.6 times more MMDs were mapped during interglacials, contributing to a 3.5 times higher sediment volume. The main reason for this large difference is that a significant increase in plastic flows were formed during interglacials, which account for a much larger volume of sediments when compared with the glacial intervals characterized by increased amount of turbidites. It appears that the most important source areas for MMDs are located at the northern and western shores. Cycles of lake level changes caused by variations in climate conditions between glacials and interglacials are likely the main trigger mechanism for the generation of these MMDs. The climate-dependent genesis and partly erosive potential influencing the sedimentary record contain implications to consider for future paleo-environmental reconstructions in lacustrine settings.