Strong offshore wind events (SOWEs) occur frequently near the Antarctic coast during austral winter. These wind events are typically associated with passage of synoptic- or meso-scale cyclones, which interact with the katabatic wind field and affect sea ice and oceanic processes in coastal polynyas. Based on numerical simulations from the coupled Finite Element Sea-ice Ocean Model (FESOM) driven by the CORE-II forcing, two coastal polynyas along the East Antarctica coast––the Prydz Bay Polynya and the Shackleton Polynya are selected to examine the response of sea ice and oceanic properties to SOWEs. In these polynyas, the southern or western flanks of cyclones play a crucial role in increasing the offshore winds depending on the local topography. Case studies for both polynyas show that during SOWEs, when the wind speed is 2–3 times higher than normal values, the offshore component of sea ice velocity can increase by 3–4 times. Sea ice concentration can decrease by 20–40%, and sea ice production can increase up to two to four folds. SOWEs increase surface salinity variability and mixed layer depth, and such effects may persist for 5–10 days. Formation of high salinity shelf water (HSSW) is detected in the coastal regions from surface to 800 m after 10–15 days of the SOWEs, while the HSSW features in deep layers exhibit weak response on the synoptic time scale. HSSW formation averaged over winter is notably greater in years with longer duration of SOWEs.