There is a tendency to farm fish in low turbidity water when production takes place in the land-based recirculating aquaculture systems (RAS). However, the effect of water turbidity on stress and performance is unknown for many species cultured in RAS. The effect of different turbidity treatments as Formazine Attenuation Units (0 FAU, 15 FAU, and 38 FAU) on feed intake performance (latency, total feeding time, and total feed intake) and physiological blood stress parameters (cortisol, lactate, and glucose) in medium-sized pikeperch ((Sander lucioperca) n = 27, undetermined sex and age) of initial body weights of 508.13 g ± 83 g (at FAU 0, 15, and 38, respectively) was investigated. The rearing system consisted of 9 rectangular tanks (200 L per tank). Fish were housed individually (n = 1, per tank, n replicates per treatment = 9). All tanks were connected to a recirculation system equipped with a moving bed biofilter. Feed intake in pikeperch kept at low turbidity (0 FAU) was 25% lower than pikeperch kept at high turbidity (38 FAU) (P < 0.01) and also significantly (10.5%) lower compared to feed intake in pikeperch kept at intermediate turbidity (15 FAU) (P < 0.01 for 0 FAU vs. 15 FAU, feed intake sign. Value as the main effect is P < 0.01). Pikeperch kept at low turbidity showed significantly slower feeding response (latency time) towards pellets entering the tank, shorter feeding times (both P < 0.05), and higher glucose blood concentration (73%) in contrast to pikeperch kept at highest turbidity. A reduction of 25% feed intake has obvious economic consequences for any fish farm and present data strongly emphasize the importance of considering the species-specific biology in future RAS farming.