The tropical western Pacific is recognized as an important region for stratosphere-troposphere exchange but lies in a data-sparse location that had a measurement gap in the global ozone sounding network. The Palau Atmospheric Observatory (PAO, approx. 7.3 N, 134.5 E) was established to study the atmospheric composition above the remote tropical western Pacific with a comprehensive instrumental setup. Since 2016, two laboratory containers in Palau host a Fourier transform infrared spectrometer; a lidar (micro-lidar until 2016, cloud and aerosol lidar from 2018); a Pandora 2S photometer; and laboratory space for weather balloon soundings with ozone, water vapor, aerosol, and radiosondes. In this analysis, we focus on the continuous, fortnightly ozone sounding program with electrochemical concentration cell (ECC) ozonesondes. The aim of this study is to introduce the PAO and its research potential, present the first observation of the typical seasonal cycle of tropospheric ozone in the tropical western Pacific based on a multiannual record of in situ observations, and investigate major drivers of variability and seasonal variation from January 2016 until December 2021 related to the large-scale atmospheric circulation. We present the PAO ozone (O3) volume mixing ratios (VMR) and relative humidity (RH) time series complemented by other observations. The site is exposed to year-round high convective activity reflected in dominating low O3 VMR and high RH. In 2016, the impact of the strong El Niño is evident as a particularly dry, ozone-rich episode. The main modulator of annual tropospheric O3 variability is identified as the movement of the Intertropical Convergence Zone (ITCZ), with the lowest O3 VMR in the free troposphere during the ITCZ position north of Palau. An analysis of the relation of O3 and RH for the PAO and selected sites from the Southern Hemispheric Additional Ozonesondes (SHADOZ) network reveals three different regimes. Palau's O3/RH distribution resembles the one in Fiji, Java and American Samoa but is unique in its seasonality and its comparably narrow Gaussian distribution around low O3 VMR and the evenly distributed RH. A previously found bimodal distribution of O3 VMR and RH could not be seen for the full Palau record but only during specific seasons and years. Due to its unique remote location, Palau is an ideal atmospheric background site to detect changes in air dynamics imprinted on the chemical composition of the tropospheric column. The efforts to establish, run and maintain the PAO have succeeded to fill an observational gap in the remote tropical western Pacific and give good prospects for ongoing operations. The ECC sonde record will be integrated into the SHADOZ database in the near future.