Changing environmental conditions in Isfjorden impact the abundance and composition of fish species in this major fjord system in Svalbard. New commercially attractive species have already entered and will expand in Svalbard waters. Based on knowledge from different sources, this paper explores and discusses how fisheries may develop in Isfjorden. We found a mismatch between the current regulatory framework, which is too fragmented and complex to address increasingly intricate fisheries matters, and the extent of ongoing changes that may result in larger opportunities for fishing activities in Svalbard waters. Drawing on the situation in Porsangerfjorden, a fjord system in Northern Norway with a boreal character, we emphasize the importance of fisheries resource management. Finally, we surmise that pressure to open fish-landing facilities on Svalbard may increase in connection with the abundance of new species of commercial interest and a stronger interest in consuming local fish products in Longyearbyen.